Help build the reference atlas
of NETosis in human disease.

Explore cellular phenotypes and larger extracellular structures through registered multichannel images.

NETosis morphology classes.

Compare representative cells across four phenotypes, including resting neutrophils, or explore larger extracellular structures.

DAPI

DAPI · Compact A

SYTOX

SYTOX · Compact A

H3Cit

H3Cit · Compact A

MPO

MPO · Compact A

Merge

Four-channel merge · Compact A

Segmentation

Segmentation contours · Compact A

A reference with biological context.

Morphology

Cellular phenotypes and the size, branching and density of extracellular structures.

Molecular features

The distribution of DNA and protein markers within each registered image.

Clinical context

Disease, treatment, time point and outcome annotations for cohort comparisons.

Bring a disease cohort into the atlas.

Help expand the reference across disease, treatment and clinical state through a cohort-based collaboration.

Your contribution

An ethically collected cohort, relevant controls or time points, and clinical annotations.

Our contribution

Study-specific imaging and analysis to connect those annotations with cellular and extracellular phenotypes.

Please exclude patient-identifying information from your proposal.