A shared process across
distinct disease contexts.

Explore how NETosis measurements could inform research in cancer, autoimmunity, thrombosis and inflammation.

Cancer & immunotherapy

How do NETosis-associated phenotypes change during treatment?

Compare H3Cit-positive event counts, MPO colocalization, DNA expansion and structure size across collection timepoints.

2026 · J Immunother Cancer — Gastric cancer immunotherapy resistance2026 · Gut — Immune escape and peritoneal metastasis2026 · Gut — Pancreatic cancer stromal reprogramming2026 · Nat Rev Cancer — NETs across cancer biology and therapy2025 · Nature — Vascular occlusion, necrosis and metastasis2025 · Cancer Cell — Omental pre-metastatic niche

Autoimmune disease

How do extracellular structures differ across disease activity and treatment?

Compare the abundance, size and morphology of intact and fragmented structures in matched samples.

2026 · Ann Rheum Dis — Gut lipoglycan–NETosis axis in lupus nephritis2026 · Ann Rheum Dis — Neutrophil–mesangial axis in lupus nephritis2025 · J Clin Invest — NET-associated CRAMP in neuroinflammation2024 · Exp Mol Med — IL-33–NET feedback in rheumatoid arthritis2024 · Kidney Int — Nrf2 regulation of NETosis in ANCA vasculitis2023 · Ann Rheum Dis — NET-associated carbamylation in rheumatoid arthritis

Immunothrombosis

Which structures carry platelet or coagulation markers?

With a study-selected panel, investigate marker colocalization, structure size and event burden.

2026 · Circ Res — Circadian NETosis and stroke perfusion2025 · Eur Heart J — Culprit-site vesicles drive NETosis after MI2024 · Nat Cardiovasc Res — Blocking NETs in cerebral cavernous malformation2021 · Circulation — Oxidized phospholipids, NETosis and arterial thrombosis2021 · Blood — NETs in chronic thrombotic vascular occlusion2017 · Science — Host DNases prevent NET-mediated vascular occlusion

Infection & systemic inflammation

How does NETosis-associated burden change during inflammation?

Track event counts, DNA expansion and morphology across serial samples.

2024 · Lancet Microbe — NET profiling in COVID-19 pulmonary aspergillosis2022 · Nat Cardiovasc Res — Platelet pyroptosis amplifies NETs in sepsis2021 · Blood — Gasdermin D blockade prevents sepsis organ dysfunction2021 · Sci Adv — NETs enhance macrophage bacterial killing2020 · Blood — NET-driven immunothrombosis in COVID-19 ARDS2019 · Sci Immunol — NETs drive inflammatory pathology in malaria

Bring structure-resolved NETosis measurement into your study.

Discuss your study